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kinase

Synonyms

Noun

1. enzyme

Usage
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies - Nature
KIRHub Opens A New Repurposing Map For Kinase Inhibitors In Lung Cancer - Oncodaily
Targeted removal of soluble Fms-like tyrosine kinase 1 in very preterm preeclampsia: a pilot trial - Nature
Kinase atlas uncovers hidden layers of cell signaling regulation - St. Jude Children's Research Hospital
Janus Kinase Inhibitor Clinical Trial Pipeline Appears Robust - openPR.com
Advancements in Protein Kinase Inhibitors: From Discovery to Clinical Applications - Science Partner Journals
Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing - Nature
Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2 - Science | AAAS
TRPM7 kinase inhibitor TG100-115 provides neuroprotection against neonatal hypoxic-ischemic brain injury - Nature
Enhancing kinase-inhibitor activity and selectivity prediction through contrastive learning - Nature
The emerging role of kinase fusion proteins in cereal immunity - Nature
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis - Nature
Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling - Nature
FDA approves 100th small-molecule kinase inhibitor - Nature
Inhibitors supercharge kinase turnover through native proteolytic circuits - Nature
Molecular recording of cellular protein kinase activity with chemical labeling - Nature
Kinase activity of DYRK family members is required for regulating primary cilium length, stability and morphology - Nature
Discovery of effectors for casein kinase signaling in the African trypanosome - Nature
14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state - Nature
A novel 5-protein kinase risk signature for predicting glioma prognosis and immunotherapy responsiveness - Nature
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature
Comprehensive evaluation of phosphoproteomic-based kinase activity inference - Nature
A web portal for exploring kinase-substrate interactions | npj Systems Biology and Applications - Nature
Reversible control of kinase signaling through chemical-induced dephosphorylation - Nature
Tandem kinase proteins across the plant kingdom - Nature
Light-gated integrator for highlighting kinase activity in living cells - Nature
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering - PNAS
Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS
A wheat tandem kinase activates an NLR to trigger immunity - Science | AAAS
Human DNA-dependent protein kinase activation mechanism - Nature
Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N - Nature
Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets - Nature
Kinase drug discovery 20 years after imatinib: progress and future directions - Nature
Trends in kinase drug discovery: targets, indications and inhibitor design - Nature
Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists - Nature
Defining a new nomenclature for the structures of active and inactive kinases - PNAS
Robust inference of kinase activity using functional networks - Nature
Aurora A kinase activation: Different means to different ends - Rockefeller University Press
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases - PNAS
Activation of the essential kinase PDK1 by phosphoinositide-driven trans -autophosphorylation - Nature
Mechanisms of Resistance to Noncovalent Bruton’s Tyrosine Kinase Inhibitors - The New England Journal of Medicine
Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers - Nature
PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase - PNAS
Pharmacological approaches to understanding protein kinase signaling networks - Frontiers
LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1 - Nature
Kinase inhibitors: the road ahead - Nature
Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites - Nature
Mechanism of activation and autophosphorylation of a histidine kinase - Nature
Cdc2-like kinases: structure, biological function and therapeutic targets for diseases - Nature
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP - PNAS
The Protein Kinase Complement of the Human Genome - Science | AAAS
Role of protein kinase PLK1 in the epigenetic maintenance of centromeres - Science | AAAS
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein kinase 1 - PNAS
Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates - PNAS
Targeting cancer with small molecule kinase inhibitors - Nature
Discovering the first tyrosine kinase - PNAS
Subcellular partitioning of protein kinase activity revealed by functional kinome profiling - Nature
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure - The New England Journal of Medicine
Structural and mechanistic insights into mechanoactivation of focal adhesion kinase - PNAS
Research shows why cancer stops responding to kinase-blocking drugs and comes back stronger - National Science Foundation (.gov)
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation - Science | AAAS
Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling - PNAS
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease - Nature
HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation - Nature
PKR: A Kinase to Remember - Frontiers
Kinase drug discovery 20 years after imatinib - Nature
De novo design of tyrosine and serine kinase-driven protein switches - Nature
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology - Nature
Inhibitors targeting Bruton’s tyrosine kinase in cancers: drug development advances - Nature
Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase - Nature
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells - PNAS
Calibrated geometric deep learning improves kinase–drug binding predictions - Nature
A historical overview of protein kinases and their targeted small molecule inhibitors - ScienceDirect.com
Shutting Down a ‘Dark Kinase’ May Defeat Treatment-Resistant Cancers - Duke University School of Medicine
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions - Nature
Deep learning enables rapid identification of potent DDR1 kinase inhibitors - Nature
Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix - Nature
Activation pathway of Src kinase reveals intermediate states as targets for drug design - Nature
Transitions to catalytically inactive conformations in EGFR kinase - PNAS
A noncanonical sequence phosphorylated by casein kinase 1 in β-catenin may play a role in casein kinase 1 targeting of important signaling proteins - PNAS
Regulation of the p21-activated kinase (PAK) by a human Gβ-like WD-repeat protein, hPIP1 - PNAS
Evidence that phytochrome functions as a protein kinase in plant light signalling - Nature
The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis - Nature
Requirement of protein kinase D1 for pathological cardiac remodeling - PNAS
Targets mapped for almost all human kinase enzymes - Nature
Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex - Science | AAAS
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression - PNAS
A dynamically coupled allosteric network underlies binding cooperativity in Src kinase - Nature
Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function - PNAS
Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis - Nature
Selective inhibition of the kinase DYRK1A by targeting its folding process - Nature
Revisiting protein kinase–substrate interactions: Toward therapeutic development - Science | AAAS
Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry - Nature
Research Reveals Why Cancers Stop Responding to Kinase-Blocking Drugs and Come Back Stronger - New York University
Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants - PNAS
Plant mitogen-activated protein kinase cascades: Negative regulatory roles turn out positive - PNAS
A chemical switch for inhibitor-sensitive alleles of any protein kinase - Nature
Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway - PNAS
A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane - PNAS
c-Src protein kinase inhibitors block assembly and maturation of dengue virus - PNAS
Foreign Language Equivalents
Foreign Language Equivalents of 'kinase'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
,   kinas,   kianse,   knase,   kinse,   kinasse,   kinaes,   kinaase,   kinae,   kinaae,   kinasee,   kimase,   kinsae,   kibase,   kinnase,   kinasw,   kinasr,   kniase,   kiase,   kinade,   kunase,   inase,   kkinase,   jinase,   kiinase,   kinsse,   konase,   iknase,   linase
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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