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fibril
Synonyms
Noun
1. filament
2. strand, fiber, fibre
Usage
CARES Phase III clinical programme did not meet primary endpoint in overall light chain amyloidosis population, however, demonstrated anselamimab as potential first anti-fibril therapy in kappa light chain amyloidosis - AstraZeneca
Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122Δ amyloidosis - Nature
Naturally occurring molecule can stop Alzheimer's-linked fibrils from forming - MSN
The temperature dependence of amyloid β solubility reveals the hydrophobic effect as the main driving force for fibril formation - PNAS
Common Mechanism Underlying Synaptic Dysfunction Caused by Preformed Fibril-Induced Accumulation of α-Synuclein or Tau in a Culture Propagation Model - Journal of Neuroscience
Anti-Fibril Depleters: The Dawn of a New Treatment Era in Transthyretin Amyloid Cardiomyopathy? - American Heart Association Journals
L-arginine stabilizes protein droplets and prevents harmful fibril formation - News-Medical
Neurimmune and AstraZeneca Expand Efforts to Accelerate Fibril-Depleting Therapies - BioPharm International
TTR fibrils share common heart structure in ATTR amyloidosis - Amyloidosis News Today
Structural basis for amyloid fibril assembly by the master cell-signaling regulator receptor-interacting protein kinase 1 - Nature
Biopsy-resolved cryo-EM structures of amyloid fibrils provide molecular insights into AL amyloidosis - PNAS
Energetic profiling reveals thermodynamic principles underlying amyloid fibril maturation - Nature
FibrilPaint to determine the length of Tau amyloids in fluids - PNAS
Structural defects in amyloid-β fibrils drive secondary nucleation - Nature
fibril populations assembled in vitro reveal rare species that resemble ex vivo amyloid polymorphs from human brains - Nature
High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs - Nature
Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation - Nature
Cracking the code of native amyloid fibrils: advances and next steps to enable pathology-informed therapeutic and diagnostic - Nature
Apolipoprotein A-IV fibrils: structural diagnosis of mixed cardiac amyloidosis - Nature
Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration - Nature
Impact of α-synuclein fibril structure on seeding activity in experimental models of Parkinson’s disease - Nature
Cross-linking of collagen fibrils leads to preferential gap zone mineralization in vitro - PNAS
Design of Ig-like binders targeting α-synuclein fibril for mitigating its pathological activities - Nature
327 Cerebrovascular disease modifies TMEM106B fibril accumulation in neurodegeneration - Cambridge University Press & Assessment
Competition Between Liquid-Liquid Crystalline Phase Separation (LLCPS) and Liquid-Liquid Phase Separation (LLPS) in Amyloid Fibril Colloidal Systems - Wiley
Anti-Fibril Depleters: The Dawn of a New Treatment Era in Transthyretin Amyloid Cardiomyopathy? - American Heart Association Journals
Biopsy-derived cryo-EM structures reveal patient-specific amyloid fibrils - Medical Xpress
Thermal effects induced by high-intensity ultrasound on the formation of whey protein isolate fibrils - ScienceDirect.com
New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples - News-Medical
Cryo-EM structure of amyloid fibrils formed by full-length human αA-crystallin with pathogenic mutation R116C - Nature
How Hydration Weakens Collagen: A Mesoscale Energy Decomposition of Type I and Type II Fibrils - Science Partner Journals
Mechanism of Self-Assembly of the Gonadropin Releasing Hormone Antagonist Teverelix into Amyloid Fibrils - ACS Publications
Investigating the selective ion adsorption performance of silver nanoparticles capped amyloid fibril aerogels - ScienceDirect.com
How short peptides disassemble tau fibrils in Alzheimer’s disease - Nature
Three‐Dimensional Visualization and Proteomic Analysis of Human Cardiac Transthyretin Amyloidosis Tissue Reveals Microangiopathy and Capillary Occlusion - American Heart Association Journals
Researchers use NVST high-resolution data to study chromospheric fibrils around quiescent filament - Phys.org
Co‐Assemblies Regulate the Catalytic Activity of Peptide Fibrils - Wiley Online Library
Scientists melt early protein clumps and shut down Alzheimer’s damage - ScienceDaily
AstraZeneca returns to Neurimmune with $780M bet on AL amyloidosis - FirstWord Pharma
Structural insights into Escherichia coli CsgA amyloid fibril assembly revisited - ASM Journals
Scientists Discover Natural Molecule That Stops Alzheimer’s Protein Clumps From Forming - SciTechDaily
Review highlights antimicrobial peptides as cross-seeding modulators at the neurodegenerative–infectious interface - EurekAlert!
How amyloid fibrils formed by RIPK1 and RIPK3 spread cell death between neighboring cells - Phys.org
Early dementia detection gets a bright new tool - ioplus.nl
A structural rationale for reversible vs irreversible amyloid fibril formation from a single protein - Nature
Scientists Uncover a Hidden Early Stage of Alzheimer’s That They Can Stop - SciTechDaily
Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation - Science | AAAS
Pulsed electric field facilitated fibrillation of soy protein isolate: preparation, characterization, and functional properties - ScienceDirect.com
Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis - Nature
Mechanism of amyloid fibril formation triggered by breakdown of supersaturation - Nature
CARES Phase III clinical programme did not meet primary endpoint in overall AL amyloidosis population, however, demonstrated anselamimab as potential first anti-fibril therapy in kappa AL amyloidosis - Cision News
Cryo-EM structure of a lysozyme-derived amyloid fibril from hereditary amyloidosis - Nature
A Self-Assembling Peptide with Nanoparticle-to-Fibril Transformation Exhibits Multimodal Antimicrobial Activity through Membrane Disruption and Quorum-Sensing Inhibition - Wiley Online Library
Hairpin trimer transition state of amyloid fibril - Nature
In Place of a Miracle Drug, Attacking Alzheimer’s With Infrared Lasers? - Being Patient
Scientists ID compounds that target amyloid fibrils in Alzheimer's, other brain diseases - UCLA Health
Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis - Nature
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis - Nature
Amyloid fibril structures and ferroptosis activation induced by ALS-causing SOD1 mutations - Science | AAAS
Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions - Nature
α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice - Nature
Mechanisms of enhanced aggregation and fibril formation of Parkinson’s disease-related variants of α-synuclein - Nature
Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis - Nature
The mechanism of amyloid fibril growth from Φ -value analysis - Nature
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis | Communications Biology - Nature
A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease - Nature
α-Synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased lipid-associated fibril uptake into iPSC-derived neurons | Communications Biology - Nature
Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43 - Nature
Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis - Nature
Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis - Nature
Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue - PNAS
Structural insights into α-synuclein monomer–fibril interactions - PNAS
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40) - Nature
Physical basis of amyloid fibril polymorphism - Nature
Cryo-EM structure of a catalytic amyloid fibril - Nature
A Sodiophilic Amyloid Fibril Modified Separator for Dendrite‐Free Sodium‐Metal Batteries - Wiley
Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion - Nature
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue - Nature
Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology - Nature
The 3D structure of lipidic fibrils of α-synuclein - Nature
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform - Nature
Amyloid β 42 fibril structure based on small-angle scattering - PNAS
Protein fibril length in cerebrospinal fluid is increased in Alzheimer’s disease | Communications Biology - Nature
Amyloid fibril structure from the vascular variant of systemic AA amyloidosis - Nature
The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism - Nature
Network Hamiltonian models reveal pathways to amyloid fibril formation - Nature
Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein - Nature
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy - Nature
Amyloid-β oligomers, curvilinear and annular assemblies, imaged by cryo-ET, cryo-EM, and AFM - Science | AAAS
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends - Nature
The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils - PNAS
Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue - Nature
Structural insight into Escherichia coli CsgA amyloid fibril assembly | mBio - ASM Journals
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids - Nature
Time-course remodeling and pathology intervention of α-synuclein amyloid fibril by heparin and heparin-like oligosaccharides - Nature
Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly - Nature
Structural basis for the inhibition of IAPP fibril formation by the co-chaperonin prefoldin - Nature
Quantification of amyloid fibril polymorphism by nano-morphometry reveals the individuality of filament assembly - Nature
AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils - Nature
Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding - Nature
Foreign Language Equivalents
Foreign Language Equivalents of 'fibril'
Language
Equivalent
Language
Equivalent
French
Spanish
Misspellings - Typos
dibril, fibriil, fbiril, finril, fibrol, ffibril, fivril, fobril, fibrli, firbil, fiibril, ibril, fibri, fibbril, fibeil, fbril, fibirl, fibrril, fibrl, fibri;, fibrul, ifbril, fubril, fibtil, gibril, fibrill, fibil, firil, fibrik
Words Starting with Letter - 'A'
a
a battery
a billion
a bit
a bit much
a capella singing
a cappella singing
a couple of
a few
a fortiori
a good deal
a great deal
a horizon
a hundred
a hundred and one
a hundred thousand
a hundred times
a kempis
a la carte
a la mode
a level
a little
a lot
a million
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