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cox-2
Synonyms
Noun
1. cyclooxygenase-2
2. Cox-2, cyclooxygenase, Cox
Usage
Figure 4. - Journal of Neuroscience
Degree of Cyclooxygenase-2 Inhibition Modulates Blood Pressure Response - American Heart Association Journals
Ecto-5ʹ-nucleotidase/CD73 reduces COX-2 expression in activated macrophages - Nature
COX-2-Selective NSAIDs a Better Choice in DOAC-Treated AF Patients - TCTMD.com
Judicial confirmation committee endorses Gov. Cox’s 2 Utah Supreme Court picks - Utah News Dispatch
Targeting COX-2 to Alleviate Depressive Phenotypes: Etoricoxib’s Antidepressant Effects in Chronic Unpredictable Mild Stress-Exposed Mice - Cureus
THC-anti-inflammatory drug pairing shows Alzheimer’s prevention potential - UT Health San Antonio
Computational strategies for unraveling insights from known inhibitors for further lead optimization: A case study on Celecoxib analogues - Nature
Max W Cox II Obituary Oct 15, 2025 - Miller Funeral Home and Crematory
Reduced expression of UPF1 promotes tumor progression through stabilizing COX-2 mRNA in nasopharyngeal carcinoma - Frontiers
Immunohistochemical expression of COX-2, Ki-67, Bcl-2, Bax, VEGF and CD105 according to histological grading in oral squamous cell carcinoma - www.elsevier.com
Pyrazole–pyrazoline derivatives as next-generation anti-inflammatory agents - News-Medical
Moving up top from defender, Cohen Cox wastes little time in scoring for Lincoln-Way West. ‘I couldn’t wait.’ - Chicago Tribune
Cyclooxygenase-2 as a therapeutic target against human breast cancer: A comprehensive review - Wiley Interdisciplinary Reviews
COX-2/PGE₂ signaling drives Toxocara canis -induced lung pathology by enhancing plasminogen activator activity and collagen VI degradation - Nature
Regulatory mechanisms of luteolin in inflammatory respiratory diseases - Frontiers
The interplay between COX-2, chemotherapeutic drugs, and chemoresistance in colon cancer - Nature
Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations - Nature
Dual anti-inflammatory activities of COX-2/5-LOX driven by kratom alkaloid extracts in lipopolysaccharide-induced RAW 264.7 cells | Scientific Reports - Nature
Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases | Communications Biology - Nature
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis - PNAS
The roles of COX-2 in protozoan infection - Frontiers
Administration of a combination of COX-2/TGF-β1 siRNAs induces hypertrophic scar fibroblast apoptosis through a TP53 mediated caspase pathway - Nature
Biology of cyclooxygenase-2: An application in depression therapeutics - Frontiers
Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies - Nature
Raging the War Against Inflammation With Natural Products - Frontiers
Cyclooxygenase-2 Selectively Controls Renal Blood Flow Through a Novel PPARβ/δ-Dependent Vasodilator Pathway - American Heart Association Journals
Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate - PNAS
Watch: Moment Sara Cox crosses finish line after 135-mile charity run - BBC
Cyclooxygenase-2 induces neoplastic transformation by inhibiting p53-dependent oncogene-induced senescence - Nature
Receptor-Driven COX-2–Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis - American Heart Association Journals
COX-2, the dominant source of prostacyclin - PNAS
Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling - Nature
Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype - Nature
Glucocorticoids alleviate particulate matter-induced COX-2 expression and mitochondrial dysfunction through the Bcl-2/GR complex in A549 cells - Nature
Lipid droplet biogenesis and COX-2 pathway activation are triggered by Barrett’s esophagus and adenocarcinoma, but not esophageal squamous cell carcinoma risk factors - Nature
COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma - Nature
A pilot study to examine the association between COX-2 rs5275 polymorphism and the response to repetitive transcranial stimulation in schizophrenia - Nature
Integrated Pathways of COX-2 and mTOR: Roles in Cell Sensing and Alzheimer’s Disease - Frontiers
Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor - Nature
Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study - Nature
Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression - PNAS
Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia - Leukemia - Nature
Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of COX-2 - The New England Journal of Medicine
Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations - Nature
Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation - Nature
Cyclooxygenase (COX)-2 modulates Toxoplasma gondii infection, immune response and lipid droplets formation in human trophoblast cells and villous explants - Nature
The yin and yang of COX-2 - Vanderbilt Health News
Inhibition of cyclooxygenase-2 by NS398 attenuates noise-induced hearing loss in mice - Nature
Vitamin D stimulates miR-26b-5p to inhibit placental COX-2 expression in preeclampsia | Scientific Reports - Nature
Elevated COX-2 Expression Promotes Angiogenesis Through EGFR/p38-MAPK/Sp1-Dependent Signalling in Pancreatic Cancer | Scientific Reports - Nature
Inhibition of NF-kB and COX-2 by andrographolide regulates the progression of cervical cancer by promoting PTEN expression and suppressing PI3K/AKT signalling pathway - Nature
Natural Cyclooxygenase-2 Inhibitors Synergize With Butyrate to Augment Chicken Host Defense Peptide Gene Expression - Frontiers
Cyclooxygenase‐2 in gastrointestinal malignancies - Wiley & Sons
Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer - Nature
miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor - Nature
Patent Headache for Rochester University - Science | AAAS
Safety of COX-2 Inhibitors in Osteoarthritis Examined - Rheumatology Advisor
Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in mice - Nature
Role of water in cyclooxygenase catalysis and design of anti-inflammatory agents targeting two sites of the enzyme - Nature
Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis - PNAS
COX-2 radiotracer could pinpoint very early stages of neurodegenerative diseases - Chemical & Engineering News
The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts - Nature
COX-2 Inhibitors – Is there cause for concern? - Nature
Role of Modulator of Inflammation Cyclooxygenase-2 in Gammaherpesvirus Mediated Tumorigenesis - Frontiers
Ganoderma cochlear Metabolites as Probes to Identify a COX-2 Active Site and as in Vitro and in Vivo Anti-Inflammatory Agents - ACS Publications
PET measurement of cyclooxygenase-2 (COX-2) with 11C-MC1 in healthy human brain - Journal of Nuclear Medicine
Complications of the COX-2 Inhibitors Parecoxib and Valdecoxib after Cardiac Surgery - The New England Journal of Medicine
COX-2 induces oncogenic micro RNA miR655 in human breast cancer - Nature
R )-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2 - Nature
Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch - PNAS
Synergy of Physico-chemical and Biological Experiments for Developing a Cyclooxygenase-2 Inhibitor - Nature
In situ click chemistry generation of cyclooxygenase-2 inhibitors - Nature
Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming - Nature
Differences in COX-1 and COX-2 further described - Vanderbilt Health News
COX-2 Inhibitors and Early Failure of Free Vascular Flaps - The New England Journal of Medicine
COX Inhibitors and Thromboregulation - The New England Journal of Medicine
A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors - Nature
Comparative population pharmacokinetics and absolute oral bioavailability of COX-2 selective inhibitors celecoxib, mavacoxib and meloxicam in cockatiels ( Nymphicus hollandicus - Nature
(+/−)-Lucidumone, a COX-2 Inhibitory Caged Fungal Meroterpenoid from Ganoderma lucidum - ACS Publications
Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression - Nature
The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway - Nature
No CV Safety Differences for COX-2 Inhibitor vs Other NSAIDs in PRECISION - TCTMD.com
New Enzyme Might Relieve Research Headache - Science | AAAS
Cyclooxygenase‐2 facilitates dengue virus replication and serves as a potential target for developing antiviral agents - Nature
Potential use of COX-2–aromatase inhibitor combinations in breast cancer - Nature
Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90 - Science | AAAS
Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes - Nature
Reduced susceptibility to ischemic brain injury and N-methyl-d-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice - PNAS
COX-2 and beyond: approaches to prostaglandin inhibition in human disease - Nature
Prostaglandin H2 Synthase (COX) - UCL | University College London
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis - The New England Journal of Medicine
Lack of effect of Imrecoxib, an innovative and moderate COX-2 inhibitor, on pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers - Nature
Perioperative COX2 and β-adrenergic blockade improves biomarkers of tumor metastasis, immunity, and inflammation in colorectal cancer: A randomized controlled trial - Wiley & Sons
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation - Nature
Ask the Doctors - How does meloxicam ease joint pain? - UCLA Health
COX-2 as a multifunctional neuronal modulator - Nature
COX-2 and COX-1 Inhibition Rates in Diclofenac Sodium Formulations - Physician's Weekly
COX-2 Inhibitors, Aspirin, and Other Potential Anti-Inflammatory Treatments for Psychiatric Disorders - Frontiers
Nociception in cyclooxygenase isozyme-deficient mice - PNAS
Foreign Language Equivalents
Foreign Language Equivalents of 'cox-2'
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Misspellings - Typos
cox2, cox2-, cxo-2, cox-, ox-2, cox--2, cpx-2, cix-2, coox-2, co-2, cox-22, cox-3, ocx-2, coz-2, ccox-2, cx-2, co-x2, coxx-2, vox-2, xox-2, coc-2
Words Starting with Letter - 'A'
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