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caspase

Synonyms

Noun

1. protease

2. peptidase, proteinase, proteolytic enzyme

Usage
Pancreatic Cancer Cell Death Triggered by Caspase‑8 Blockade in Preclinical Models - Genetic Engineering and Biotechnology News
Caspase-8 Identified as Achilles Heel in KRAS-Driven Pancreatic Cancer - Technology Networks
Caspase-3 cleaves and activates the NADase SARM1 to promote apoptosis, linking two cell death mechanisms - PNAS
VENT-04 - Ventus Therapeutics
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection - Nature
Extracellular caspase-1: a critical inducer and a therapeutic target of lung injury in gut ischemia-reperfusion - Frontiers
Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induced Obesity - Wiley
Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3 - ASM Journals
NLRP3/Caspase-1 Regulate Macrophage Efferocytosis by Modulating ADAM17-Mediated MerTK Cleavage in Liver Ischemia–Reperfusion Injury - Science Partner Journals
Caspase-8 comes in from the CYLD - Nature
Targeting NLRP3/caspase-1/GSDMD to treat inner ear injury from labyrinthine hemorrhage - ScienceDirect
Ventus Therapeutics Announces Nomination of VENT-04, a First-in-Class, Oral, Small-Molecule Caspase-4/5 Inhibitor, as a Development Candidate - Business Wire
Secondary Necrosis Following Caspase-Activation can Occur Independently of Gasdermin E - Wiley
Plant caspase-like proteins: from function identification to application in winter rapeseed genetic breeding - Frontiers
Non-pyroptotic caspase-11 activity regulates osteoclastogenesis and pathological bone loss - Nature
Caspase-mediated DDX46 cleavage unchains antiviral immunity - ASM Journals
Dipeptidyl Peptidase 4 Mediated Caspase-8 Affects Cognitive Impairment in Mice With Alzheimer's Disease - Wiley
Regulation of inflammatory processes by caspases - Nature
Caspases as master regulators of programmed cell death: apoptosis, pyroptosis and beyond - Nature
In-Field Molecular Diagnostics of Plant Pathogens Using Bioluminescent CRISPR-Guided Caspase Assay - Wiley Online Library
IFN-γ-mediated suppression of Caspase-7 exacerbates acute lung injury induced by CAR-T cells - ScienceDirect
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis - Rockefeller University Press
Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia - Nature
Caspase-2 protects against ferroptotic cell death - Cell Death & Disease - Nature
TNF switches homeostatic efferocytosis to lytic caspase-8–dependent pyroptosis and IL-1β maturation - Science | AAAS
Ventus Therapeutics Announces Nature Reviews Immunology Publication Demonstrating the Promise of Caspase-4/5 as Therapeutic Targets - Ventus Therapeutics
Arginine methylation of caspase-8 controls life/death decisions in extrinsic apoptotic networks - Nature
A long way to go: caspase inhibitors in clinical use - Nature
Caspase-7 activates ASM to repair gasdermin and perforin pores - Nature
Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease - Nature
Drug-induced oxidative stress actively prevents caspase activation and hepatocyte apoptosis - Nature
The p53-caspase-2 axis in the cell cycle and DNA damage response - Nature
The prodomain of caspase-3 regulates its own removal and caspase activation - Nature
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7 - Science | AAAS
Caspase-1 initiates apoptosis in the absence of gasdermin D - Nature
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death - Nature
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells - Science | AAAS
Apoptosis regulation by subcellular relocation of caspases - Nature
Caspases and their substrates - Cell Death & Differentiation - Nature
Caspase 3 activity is required for skeletal muscle differentiation - PNAS
Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth - Nature
Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma - Nature
Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks - PNAS
Caspase involvement in autophagy - Nature
A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death | Scientific Reports - Nature
Caspase-11 promotes allergic airway inflammation - Nature
Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide - Nature
Inflammatory caspase substrate specificities - ASM Journals
Non-lethal roles of the initiator caspase Dronc in Drosophila - Frontiers
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation - Rockefeller University Press
Evolution of caspase-mediated cell death and differentiation: twins separated at birth - Nature
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin - Nature
Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions - Rockefeller University Press
Caspase-dependent non-apoptotic processes in development - Nature
Caspase-2 Substrates: To Apoptosis, Cell Cycle Control, and Beyond - Frontiers
Old, new and emerging functions of caspases - Cell Death & Differentiation - Nature
Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme - PNAS
The road to death: Caspases, cleavage, and pores - Science | AAAS
The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions | Cell Death & Disease - Nature
Caspase-10 is an initiator caspase in death receptor signaling - PNAS
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia - Nature
Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy - PNAS
FLIPL permits apoptotic and inflammatory signaling and inhibits necroptosis in mice without Caspase-8 oligomerization - PNAS
Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms - Journal of Neuroscience
Dimer formation drives the activation of the cell death protease caspase 9 - PNAS
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics - Nature
Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage - Nature
Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment - Nature
Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis - Nature
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate - Nature
Caspase-2: the orphan caspase - Nature
Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth - PNAS
Caspase-mediated LPS sensing and pyroptosis signaling in Hydra - Science | AAAS
Neuronal caspase-3 signaling: not only cell death - Nature
Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis - PNAS
Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells - ASM Journals
A new type of Caspase-1 upon recognizing bacteria inhibits GSDME-dependent histone modification and NF-κB signaling - Nature
Suppression of caspase 8 activity by a coronin 1–PI3Kδ pathway promotes T cell survival independently of TCR and IL-7 signaling - Science | AAAS
Functional consequences of caspase activation in cardiac myocytes - PNAS
Caspase activation pathways: some recent progress - Nature
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis - Nature
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling - PNAS
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma - PNAS
Caspase function in programmed cell death - Nature
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state - PNAS
Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity - Nature
Caspase-3 cleaves hnRNP K in erythroid differentiation - Nature
Oligomerization and activation of caspase-9, induced by Apaf-1 CARD - PNAS
The biochemical mechanism of caspase-2 activation - Nature
Caspase-8 has dual roles in regulatory T cell homeostasis balancing immunity to infection and collateral inflammatory damage - Science | AAAS
Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors - Nature
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function - PNAS
Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis - Nature
Glycolysis promotes caspase-3 activation in lipid rafts in T cells - Nature
Caspase-14 and epidermis maturation - Nature
RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8 - Science | AAAS
A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells - American Physiological Society Journal
Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment - Nature
Semaphorin-Mediated Corticospinal Axon Elimination Depends on the Activity-Induced Bax/Bak-Caspase Pathway - Journal of Neuroscience
Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach - Nature
Foreign Language Equivalents
Foreign Language Equivalents of 'caspase'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
aspase,   xaspase,   caapase,   caspsae,   caspse,   capsase,   capase,   caspade,   caspaes,   caspasw,   cspase,   caspaae,   caspaase,   csapase,   casapse,   caspae,   vaspase,   casppase,   casspase,   ccaspase,   casoase,   csspase,   caspasee,   caaspase,   cas[ase,   acspase,   caspsse,   caspas,   cadpase,   caspasr,   casase,   caspasse
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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